Control of Colinearity in AbdB Genes of the Mouse HoxD Complex

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Breaking Colinearity in the Mouse HoxD Complex

Vertebrate Hox genes are activated in a spatiotemporal sequence that reflects their clustered organization. While this colinear relationship is a property of most metazoans with an anterior to posterior polarity, the underlying molecular mechanisms are unknown. Previous work suggested that Hox genes were made progressively available for transcription in the course of gastrulation, implying the ...

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ژورنال

عنوان ژورنال: Molecular Cell

سال: 1998

ISSN: 1097-2765

DOI: 10.1016/s1097-2765(00)80029-5